Jun 22, 2023 13:28
11 mos ago
26 viewers *
French term

pourcentage de recouvrement

French to English Medical Mathematics & Statistics Validation of changes
Another question on my article on medical stats.

Par ailleurs il est conseillé de ne pas faire les mesures pour estimer le *pourcentage de recouvrement* et la variabilité dans des expériences séparées, sauf si cela impacte l’utilisation de la méthode en routine.

percentage overlap?

Discussion

Sue Davis (asker) Jun 25, 2023:
My apologies being under pressure I may not have made the nature of the work clear enough (see previous questions). It refers to the comparison of product parameters before and after a change in the process or analytics to validate the post-change product. I think overlap (between pre-change and post-change measurements) is most likely.
Daryo Jun 24, 2023:
@ Sue Davies there are some potential ambiguities.

does this "process" ("expérience") include "recovering" something? Like "recovering" a substance from a solution to measure its concentration?

With what you have given so far overlap (between ?? and ??) could make as much sense as "recovery" (of ?? from ??).

Without knowing which variables are measured and their interconnections, it's very easy to make apparently plausible but totally wrong assumptions.
Sue Davis (asker) Jun 22, 2023:
expériences = experiments run on samples using the old and the new methods
Sue Davis (asker) Jun 22, 2023:
Hi Phil, sorry it's both. It's an article on statistical methods used in the pharma industry to assess whether a product is unchanged before and after implementing a change e.g. in a process. Guess it's pharma rather than medical
philgoddard Jun 22, 2023:
It's not really clear what this is about, since you've labelled it medical AND statistics.

What are the "expériences" and the "méthode en routine"?

Proposed translations

-1
1 day 23 hrs
Selected

proportion / rate / percentage of overlap (/similarity)

if the aim is to "to assess whether a product is unchanged before and after implementing a change e.g. in a process", then

recouvrement = overlap i.e. "pourcentage de recouvrement" would be the extent of the "overlap = similarity" between a product before and after implementing a change in a process.

pourcentage de recouvrement = 100% would mean the product is exactly the same before and after a change in the process.

pourcentage de recouvrement = 0% would mean the product before and the product after changing the process have absolutely nothing in common, that after changing the process, the resulting product has been changed beyond recognition.

Doesn't matter at all what is "the product" or "the process" used to make the product. The method used is clear enough: make some changes to "the process" and mesure "le pourcentage de recouvrement" i.e. to which extent the resulting product "overlaps" with the product obtained by the same process before the change.

ALL THIS ASSUMING THAT "recouvrement" IS NOT PART OF THIS "process" which is yet to be confirmed so CL1.
Peer comment(s):

disagree Mpoma : Not in microbiology.
1 day 4 hrs
Microbiology??? All I can see here is some general statistical method for evaluating the results gained from changing **a** process. ***Would be the same no matter what the "process" is about*** - making shoes or deciding loan applications..
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4 KudoZ points awarded for this answer. Comment: "many thanks for your help"
+1
4 hrs

recovery percentage

Using Sampling Recovery Percentages
Cleaning Validation Simplified
https://cleaningvalidation.com › memos › using-sampl...
If this is the manner of using recovery percentages, then generally an acceptable percentage recovery should be 50% or greater. If recoveries of 50-65% are ...

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Note added at 4 heures (2023-06-22 18:14:38 GMT)
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https://www.quansysbio.com/support/recovery-and-linearity/
26 Sept 2022 — %Recovery = ((Observed Concentration – Endogenous Concentration)/ Spiked Diluent Concentration)*100. The mean percent recovery for any sample ...
Peer comment(s):

agree Mpoma : Done a few pharma things. I believe it's about recovering micro-organisms after experiments, something like that...
14 hrs
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3 days 3 hrs

recovery rate

The minute you said this was about pharma it was clear this was about micro-organisms. The correct term in French is "taux de recouvrement", but as it's measured in % it's fine to say "pourcentage de recouvrement".

Liz's term is close but Anglophone microbiologists use "rate".

There's a definition on this page https://www.a3p.org/determination-taux-de-recouvrement-etape...

For what is meant by "recovery" in microbiology see here: https://consultglp.com/2017/07/18/estimating-mu-for-microbio...

"Recovery is defined as “Proportion of the amount of analyte, present in or added to the analytical portion of the test material, which is extracted and presented for measurement”."
Note from asker:
sorry it isn't necessarily microbiology, I hoped answerers had seen previous questions.
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Reference comments

15 mins
Reference:

Yes, percentage overlap;

It is also advisable not to carry out measurements to estimate *percentage overlap* and variability in separate experiments, unless this impacts on the routine use of the method.
Peer comments on this reference comment:

neutral liz askew : this does not prove that pourcentage de recouvrement = percentage ovelap. You don't use any Fr refs. to prove this.
1 hr
disagree Mpoma : No, not in this pharma context. Means something specific about typical pharma experiments.
19 hrs
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1 hr
Reference:

comment

what bothers me is that I am unable to find "pourcentage de recouvrement", only "taux de recouvrement" as in:

https://hal.univ-lorraine.fr/hal-01770845/document
Figure 23 : Taux de recouvrement (%) de solutions hERG par rapport à une solution « Cal » de même concentration en CLHP-UV .

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Note added at 1 heure (2023-06-22 15:25:13 GMT)
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Probing the Interaction Between Inactivation Gating and
University of Oxford
https://www.robots.ox.ac.uk › ~thomas › Numa...
PDF
by H Numaguchi · 2000 · Cited by 112 — In summary, the findings suggest that extracellular Na hastens the development of HERG inactivation during depolarization and the ****rate of recovery****


I don't know if this is relevant
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