Glossary entry

German term or phrase:

Organtoxizität / organtoxisch

English translation:

organ toxicity / organotoxic

Added to glossary by Steffen Walter
Jun 17, 2007 07:21
16 yrs ago
German term

organtoxisch

German to English Medical Medical: Pharmaceuticals regulatory
"Aufgrund tierexperimenteller Befunde ist bei vershentlicher Einnahme grösser Mengen Erbrechen möglich. *Organtoxische* Veränderungen sind jedoch nicht zu erwarten."
I'm assuming something like "no toxic changes to organs are anticipated", but would appreciate your input.
Change log

Jun 23, 2007 13:21: Steffen Walter changed "Edited KOG entry" from "<a href="/profile/34828">Jonathan MacKerron's</a> old entry - "organtoxisch"" to ""organ toxicity/organotoxic""

Proposed translations

+1
10 mins
German term (edited): organtoxische Veränderungen
Selected

organ toxicity

IMO, "Veränderungen" is one of these words which you need not explicitly translate in many cases.
Peer comment(s):

agree casper (X)
7 hrs
Thank you, Chetan!
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4 KudoZ points awarded for this answer. Comment: "Thanks to all"
+1
13 mins

organ toxic effects are not to be expected/unlikely.

"organ toxic effects" seems to be a frequently used term in such contexts.
See, for example:
www.annals.org/cgi/content/full/124/8/726
under the heading "Metabilism and toxicity of Pennyroyal Oil" (about the middle of the article)
Peer comment(s):

agree Susanne Rindlisbacher : or: organotoxic
34 mins
Danke schön, Susanne. Schönen Sonntag!
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14 mins

tissue-specific toxicity

My first answer would have been organ-specific toxicity (see also Anne's suggestion ;-) ), but even more common is IMO tissue-specific toxicity - so I post this alternative answer:

German source text: see page 8
http://www.uni-duesseldorf.de/kojda-pharmalehrbuch/apotheken...
(page 8)

tissue-specific:
http://jpet.aspetjournals.org/cgi/reprint/282/2/1102

organ-specific:
http://iccvam.niehs.nih.gov/docs/acutetox_docs/finalrpt/fin_...
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2 hrs

organotoxic

although not that much google hits as "organ toxic", but these hits are not always representative for a term commonly used by a person skilled in the art
Peer comment(s):

neutral Cilian O'Tuama : in case you didn't notice, this was already suggested over an hour earlier
14 hrs
You are right, already from Susanne, thnx, delete my answer or not, but do not score it
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